Please don't listen this frequency more than 45 seconds at a streach without the guidance of an expert or professional. Morning & Evening are the best time to listen. Parkinson’s disease is a progressive neurodegenerative disorder that primarily affects movement control. It occurs when nerve cells in the brain, particularly in a region called the substantia nigra, gradually degenerate and die. These cells are responsible for producing dopamine, a neurotransmitter crucial for smooth and coordinated muscle movement.